Best friends come in all different shapes, sizes, personalities and sometimes disabilities. Not everyone is the same but the people who love you for who you are, are the best of friends. In this ted talk the woman on stage was originally a man but is transgender. She has a huge support system behind her, no matter what is different about her. She has people who wont judge her and will love her for her. Just like Lennie and George. In of mice and men Lennie has a disability and isn't all there in the head, though George still loves him through it all. George covers for him and does what is best for him. George is the true definition of a best friend.